产品货号：
Z14363
中文名称：
EGFR抗体
英文名称：
Anti-EGFR Antibody
产品规格：
250μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-EGFR Antibody |
| 指标别名 | EGFR;EGFR-Specific;ERBB;ERBB1;HER1;mENA;PIG61;Proto oncogene c ErbB 1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,rat |
| 应用范围 | IHC,IP,WB |
| 基因名称 | EGFR |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | This whole rabbit serum was prepared by repeated immunizations with a peptide synthesized using conventional technology.?The sequence of the epitope maps to a region near the carboxy terminus which is identical in human,mouse and rat EGFR. |
| 成分 | 0.01% (w/v) Sodium Azide |
| 纯化方式 | This antiserum is directed against human epidermal growth factor receptor (EGFR) and is useful in determining its presence in western blotting and immunoprecipitation experiments.This antibody can detect EGFR from human,mouse and rat sources.Reactivity of this antibody with EGFR from other species is unknown.No reaction is observed against ErbB-2,ErbB-3 or ErbB-4. |
| 浓度 | 85mg/mL by Refractometry |
| 产品形态 | 溶液 |
| 保存条件 | Store vial at -20℃ prior to opening.Aliquot contents and freeze at -20℃ or below for extended storage.Avoid cycles of freezing and thawing.Centrifuge product if not completely clear after standing at room temperature.This product is stable for several weeks at 4℃ as an undiluted liquid.Dilute only prior to immediate use.Expiration date is one (1) year from date of opening. |
| 背景资料 | EGFR is a transmembrane glycoprotein that is a member of a family of protein tyrosine kinases crucial to maintaining a normal balance in cell growth and development.Growth factor receptors are involved not only in promoting the proliferation of normal cells but also in the aberrant growth of many types of human tumors.For example,the epidermal growth factor receptor (EGFR) is mutated and/or over-expressed in many common solid human squamous cell carcinomas including breast,brain,bladder,lung,gastric,head & neck,esophagus,cervix,vulva,ovary,and endometrium.Over-expression of the EGFR gene occurs in carcinomas with and without gene amplification.EGFR and ErbB-2 are particularly important in breast cancer because increased production or activation has been associated with poor prognosis.EGFR belongs to a family of growth factor receptors,which also includes ErbB-2/HER-2/neu,ErbB-3/HER-3/neu and ErbB-4/HER-4/neu.EGFR can heterodimerize with each of the members of this family. |
| Uniprot ID | P00533 |
| 推荐稀释比 | ELISA:1:10,000 - 1:50,000 IHC:2.5μg/mL IP:10μL WB:1:1,000 - 1:10,000 |
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